NFL Week 15 Odds and Betting Lines

After a wild, high-scoring week of NFL action, Week 15 is coming, and we’re hoping for more of the same.

The Chiefs? Ready for the postseason after clinching a playoff spot with a last-minute doink field goal.

The Niners? Still showing signs of life, but they need every win.

The Lions? Just roaring all the way to the #1 seed in the NFC.

All the latest NFL odds for Week 15 are at Bovada, and previews and betting tips are ready right now too. Read on and get ready.

NFL Odds

View the latest NFL odds at Bovada

Los Angeles Rams (+115) at San Francisco (-135)

After a crazy, amazing 44-42 win over the Buffalo Bills, do the LA Rams have enough in the tank for a quick turnaround? It will be a thrilling Thursday Night Football game against the San Francisco 49ers.

Star wide receivers Cooper Kupp and Puka Nacua racked up 17 catches and 254 yards receiving just between the two of them.

The San Francisco 49ers, meanwhile, scored major points in their crushing of the Chicago Bears. They had a much easier time than LA did, cruising to 38 points and looking like the Niners we all expected before the season started.

In a game with evenly matched teams, it may come down to health.

The Niners still have a lot of injured starters out, and the short week won’t help them. Even Christian McCaffrey and Jordan Mason’s replacement RB, Isaac Guerendo, came down with a foot injury late into his stellar 120+ total yards performance.

The Rams, at +2.0 and +115 currently, could be the play, just by having more bodies available.

Bet on 100’s of props and all the latest lines for the Rams-49ers game now.

Buffalo Bills (+115) at Detroit Lions (-135)

This potential Super Bowl preview is a heavyweight matchup that every football fan will be watching.

The Bills, fresh – or maybe not so fresh – from a 42-point performance in a loss, head into the Lions’ den, where the crowd will be in a Ford Field frenzy. Assuming MVP front-runner Josh Allen plays at the same level he’s been at in recent weeks, this game could come down to the wire.

The Detroit Lions had the edge in becoming the Super Bowl winner when it came to NFL odds before the season started, and they’ve lived up to the hype.

The X factor for this game could be the Bills’ defense. The Rams just hung 44 points on them while making it look easy, and LA doesn’t even have all the weapons that Detroit does. Then again, in 10 of their 13 games so far this season, Josh Allen and his unsung teammates have scored at least 30 points.

That high-powered O might just be able to exploit the Lions’ injury-filled defense. They have almost twice as many defensive players on injured reserve than the next-closest team.

With tons of offense on both sides, the Bills-Lions game has hundreds of fun props to play.

Indianapolis Colts (+175) at Denver Broncos (-210)

The Broncos and Colts have a lot to play for in this battle of talented young QBs.

Indianapolis has had a rollercoaster season, but quarterback Anthony Richardson seems to have settled in after his mid-season benching. They’ve won 2 out of their last 3, and in that one loss they managed to keep the powerful Lions to a fairly low 24 points.

Sean Payton has his Broncos squad outplaying expectations this season, with rookie QB Bo Nix getting better by the week. They’ve won 3 straight, scoring an average of 36 points per game.

These teams are currently 7^th and 8^th in the playoff picture, so a head-to-head win could be crucial at the end of the NFL regular season.

With that much on the line, could the Colts cover the current +4.0 spread? Or is home field, in the cold Mile High air, along with a savvy Payton calling the shots, too much for the dome-loving Colts? The Colts are 1-4 against the spread over their last 5 games, so keep that in mind.

Bet on the Colts-Broncos spread, moneyline, and much more.

Pittsburgh Steelers (+190) at Philadelphia Eagles (-230)

Well, that was a close one for Philly fans and bettors. Especially the person who bet $3 million on the Eagles to beat the Panthers last weekend, with the Eagles barely winning despite being favored by two touchdowns.

They’ll need to be at their best in this meeting between two division leaders.

The Steelers, behind Russell Wilson’s somewhat improbably good season, are 7-1 both against the spread and straight up over their last 8 games. But Philly is a tougher test than any other opponent they have faced this year—only two of those Steelers’ wins came against teams with a winning record, and they lost to the Browns just a few weeks back.

Can Saquon put the Eagles on his back as he has all season and defeat the Steelers? It’ll be tough in this latest battle of Pennsylvania.

Pittsburgh is 4^th in the league in rushing defense. That could be an issue, with the Eagles’ passing game looking weak lately too. QB Jalen Hurts put up a meager 108 yards against the Panthers last week, and his top receiver AJ Brown was not pleased, causing possible discord in the locker room.

Philly’s defensive strength comes from its secondary, with super rookies Cooper DeJean and Quinyon Mitchell leading the way. They’ll make life tough for Russ and his receivers.

This could be a close one, but look for an angry Eagles team to come out hard at home to avenge last week’s soft performance.

Every bet you need for Steelers vs Eagles is right here at Bovada.

Green Bay Packers (-150) at Seattle Seahawks (+130)

Despite a close loss to the Lions last weekend, the Green Bay Packers (10-3) are looking like solid NFL playoff contenders.

But the Seahawks have won 4 in a row themselves, and as of right now, this matchup might be the same on Wild Card Weekend next month. The Pack is a tougher read for betting fans than their W-L record indicates. While they’re 7-3 SU in their last 10, they are a very average 5-5 ATS in that same stretch.

The Seahawks (8-5) are first in their tight division, and they need this game even more than Green Bay does. With 4 games to play, the difference between first and last in NFC West is a mere two games.

It’s the Packers defense that might be their weak link. They gave up 4 first downs on 4^th down against the Lions and are banged up.

In what should be a close game, Green Bay’s inability to shut things down in clutch moments might give a hungry Seattle squad – with close to 200 yards of offense by their backup running back last weekend – the edge.

Catch all the NFL odds, props, and bets for Green Bay vs Seattle now.

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*Odds subject to change